Nicotinamide mononucleotide, or NMN, a substance produced in our bodies and also present in food will be tested on human subjects after it showed significant results in animal models. The mechanism considered to result in anti-aging properties is the activating of a gene called sirtuin. Sirtuins are able to inhibit certain genes, including ones that promote aging. When animals were administered NMN, it was found that the compound can reverse age-related eyesight and metabolism deteriorations, improve diabetes and slow down aging. The new study will be conducted at Keio University and Washington University in St. Louis.
NMN is currently available as a supplement but no current indication for anti-aging effects can be claimed.